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POSTDOCTORAL FELLOWSHIP: iPSC MODELS FOR AUTISM

Website Oregon Health & Science University

A Postdoctoral Scholar position with a focus on applying developmental neuroscience and genomic techniques to novel induced pluripotent stem cell (iPSC) models of key autism risk genes is immediately available in the laboratory of Dr. Brian J. O’Roak in the Department of Molecular and Medical Genetics at Oregon Health & Science University (OHSU), Portland OR. Previous experiences with iPSCs, 2D neuronal differentiation, and/or 3D brain organoid (spheroid), and single-cell -omics are strongly preferred.

Highlights of Dr. O’Roak’s past research successes include: pioneering trio-based exome sequencing in simplex autism and developing new technologies for rapid and economical targeted resequencing. We are building on this experience with a strong and diverse research group focused on developing and implementing cutting-edge methods and technologies for discovery and replication, molecular diagnosis, functional dissection of pathways, and targeted therapeutics for neurodevelopmental and related disorders. This work has the potential to dramatically improve the lives of individuals affected with these currently untreatable disorders through early intervention and biologically based personal therapies.

Salary for this position aligns with the NIH Scale.

Required Qualifications

  • PhD, MD or MD/PhD in neuroscience, cell/molecular biology, genetics or related field
  • Experience in and a strong interest in induced pluripotent stem cells and developmental neuroscience
  • Demonstrated ability to work independently and learn new techniques quickly
  • Candidates must be well organized, self-motivated and dependable
  • Excellent communication skills with the ability to plan, document, analyze and report data

Preferred Qualifications

  • Intensive training in the areas of iPSCs, genetics/genomics, computer science, or bioinformatics
  • Expertise in microscopy, 2D and 3D neuronal culture
  • Previous experience analyzing –omics datasets
  • Familiarity with statistics and optimal study design

Interested candidates should email a cover letter, CV, and contact information for three references to: oroak@ohsu.edu

All are welcome

Candidates from diverse backgrounds are especially encouraged to enquire about potential funding through the OHSU Fellowship for Diversity and Inclusion by contacting OFDIR@ohsu.edu.

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.